Informant single screening questions for delirium and dementia in acute care – a cross-sectional test accuracy pilot study

Background Cognitive impairment often goes undetected in older people in hospital. Efficient screening tools are required to improve detection.<p></p> To determine diagnostic properties of two separate informant-based single screening questions for cognitive impairment (dementia and delirium) in hospitalised older people.<p></p> Methods Patients over 65 years non-electively admitted to medical or geriatric wards within a teaching hospital. Our index tests were single screening questions (SSQ), one for dementia (“How has your relative/friend’s memory changed over the past 5 years (up to just before their current illness)?”) and one for delirium (“How has your relative/friend’s memory changed with his/her current illness?”), which were assessed with informant response given on a five point Likert scale.<p></p> Any deterioration on our index tests of SSQ-dementia and SSQ-delirium was accepted as a positive screen for cognitive impairment. Scores were compared to the Informant Questionnaire for Cognitive Decline in the Elderly (IQCODE) >3.38 accepted as dementia, and Confusion Assessment Method (CAM) diagnosis of delirium. We also collected direct cognitive screening data using Mini Mental Status Examination (MMSE).<p></p> Results Informant responses were obtained in 70/161 (43.5%) patients, median age 80.8 (range:67–97) years; mean MMSE score 18.5 (SD: 8.1). The SSQ-dementia when compared to the IQCODE had a sensitivity of 83.3% and specificity of 93.1%. The SSQ-delirium when compared to CAM diagnosis had sensitivity of 76.9% and a specificity of 56.1%.<p></p> Conclusions These findings show promise for use of an informant single screening question tool as the first step in detection of dementia in older people in acute hospital care, although this approach appears to be less accurate in screening for delirium.<p></p&gt

The Corralitos Observatory program for the detection of lunar transient phenomena

This is a final report on the establishment, observing procedures, and observational results of a survey program for the detection of lunar transient phenomena (LTP's) by electro-optical image conversion means. For survey, a unique detection system with an image orthicon was used as the primary element in conjunction with a 24-in. f/20 Cassegrainian telescope. Observations in three spectral ranges, with 6,466 man-hours of observing, were actually performed during the period from October 27, 1965, to April 26, 1972. Within this entire period, no color or feature change within the detection capabilities of the instrumentation was observed, either independently or in follow up of amateur LTP reports, with the exception of one general bluing and several localized bluings (probably ascribable to the effects of the terrestrial atmosphere) that were observed solely by the Corralitos system. A table is presented indicating amateur and professional reports of LTP's and the results of efforts to confirm these reports through the Corralitos system

A robust method for measuring the Hubble parameter

We obtain a robust, non-parametric, estimate of the Hubble constant from galaxy linear diameters calibrated using HST Cepheid distances. Our method is independent of the parametric form of the diameter function and the spatial distribution of galaxies and is insensitive to Malmquist bias. We include information on the galaxy rotation velocities; unlike Tully-Fisher, however, we retain a fully non-parametric treatment. We find $H_0=66\pm6$ km/s/Mpc, somewhat larger than previous results using galaxy diameters.Comment: 4 pages, 1 figure, Cosmic Flows Workshop, Victoria B.C. Canada, July 1999, ed. S. Courteau, M. Strauss & J. Willick, ASP conf. serie